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Services available include hospital (inpatient, outpatient and observation), swing bed (skilled nursing services), dietitian and nutrition services, rehabilitation services, laboratory services, X-ray and CT services, MRI, mobile mammogram and Dexa scan, clinic services, emergency services 24/7/365, telemental health, and various outreach services.

Provides a full range of primary healthcare services including physical exams, chronic disease management, acute illness management, physicals, well child exams, children/adolescent/men/women healthcare services, immunizations, telemedicine related to medical and mental health needs, certified laboratory services, All Women Count services, assistance with Marketplace insurance enrollment, and allergy injections. Nurse triage available for after-hours calls. Situation will be assessed by a registered nurse with further guidance provided. Strives to meet the needs of all patients, including the underinsured and underserved and offers services at a reduced rate to those who qualify.

A full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Horizon Health - Martin Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Services include cancer services/oncology, cardiology, chaplain services, diabetes care, diagnostic imaging, emergency and trauma care, home health and hospice, home medical equipment, occupational health, orthopedics, pediatrics, rehabilitation services, senior services, sports medicine, telemedicine, wellness services, women's specialty services, and family medicine.

Provides primary health services free of charge for the homeless. This includes those living in shelters, transitional housing, on the streets, or doubled up with friends, neighbors, or relatives. Counseling services available.

Provides emergency care, pediatrics, family medicine, general practice medicine, inpatient and outpatient rehabilitation therapy, medical imaging, OBGYN, 3D mammography (Free mammogram and cancer screening program 'We've Got You Covered'), chemotherapy, laboratory services, internal medicine, general surgery, dialysis, home health, hospice, intensive care, outpatient treatment, same day surgery, orthopedic surgery, podiatric surgery and swing bed.

Services include behavioral health (including Substance Use Prevention), Community Health Representatives, dental care, diabetes care, health promotion/disease prevention, immunizations, laboratory, nursing, medical imaging, optometry, pharmacy (Prescription Assistance if eligible), Primary Care, public health nursing, smoking cessation, specialty clinics (e.g. OB/GYN, Mammography, Telehealth), weight loss/nutrition, well child care, women's health, and Wowasake Wellness Center

Horizon Health - De Smet Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

A Critical Access Hospital equipped with medical/surgical, pediatric, intensive/coronary care, and swing bed/intermediate care. The Wagner Community Clinic is adjacent to the hospital making it convenient to see hospital patients, share laboratory services and other diagnostic equipment.

Horizon Health - Howard Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

A full service hospital and family medicine clinic located in the community of Clear Lake, SD. The facility provides acute, emergency, and medical care.

Falls Community Health is a family practice medical clinic and dental clinic with emphasis on health promotion and disease prevention. The Community Health Center was established in 1979 with its goal being to remove the barriers, primarily financial, that exist and limit the access of lower income individuals or families seeking primary health care services.  ​Services for the general public include family health, lab radiology, well-child care, immunizations, family planning (including birth control, STD screening and treatment), patient education, and dental care. Services for established clinic patients include outpatient mental health and substance abuse counseling, psychiatry services, transportation assistance (transporter of last resort), and pharmacy assistance to clients of the Falls Community Health Care Clinic.

Horizon Health - Isabel is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Isabel is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

Horizon Health - Elk Point is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Sanford Vermillion Medical Center is a full service hospital and clinic providing the following services: 24-Hour Emergency Care, Ground and Air Ambulance support/access, medical, surgical, pediatric, and obstetrical care, outpatient nursing services (including chemotherapy), family medicine clinic, diagnostic services, home care and hospice programs, outpatient mental health counseling, rehabilitation therapies, respiratory care, acute care hours Saturday morning, Sunday afternoon, and weekday evenings, sports medicine, community health education, specialty outreach services (cardiology, diagnostic radiology, ENT surgery, general surgery, neurology, nephrology, oncology, orthopedics, podiatry, psychiatry, pulmonology, urology, and vascular surgery), and University of South Dakota student health services. Vermillion Medical Center has a teaching affiliation with USD Health Science Program.

Provides a full range of primary healthcare services including physical exams, chronic disease management, acute illness management, physicals, well child exams, children/adolescent/men/women healthcare services, immunizations, telemedicine related to medical and mental health needs, certified laboratory services, All Women Count services, assistance with Marketplace insurance enrollment, and allergy injections. Nurse triage available for after-hours calls. Situation will be assessed by a registered nurse with further guidance provided. Strives to meet the needs of all patients, including the underinsured and underserved and offers services at a reduced rate to those who qualify.

Provides primary LGBTQ+ health care for people up to the age of 21. This includes routine check-ups, sexually transmitted/HIV/pregnancy tests, and sexual health education. An in-house pharmacy is available as well as mental health counseling services. Dr. Amanda Diehl has more than 20 years of experience and trained on LGBTQ+ health care through the Fenway Institute's National LGBT Health Education Center. In addition, the entire staff has been trained to provide an affirming atmosphere for the LGBTQ+ population.

Falls Community Health is a family practice medical clinic and dental clinic with emphasis on health promotion and disease prevention. The Community Health Center was established in 1979 with its goal being to remove the barriers, primarily financial, that exist and limit the access of lower income individuals or families seeking primary health care services.  ​Services for the general public include family health, lab radiology, well-child care, immunizations, family planning (including birth control, STD screening and treatment), patient education, and dental care. Services for established clinic patients include outpatient mental health and substance abuse counseling, psychiatry services, transportation assistance (transporter of last resort), and pharmacy assistance to clients of the Falls Community Health Care Clinic.

Horizon Health - Yankton Medical offers Medical care (behavioral health, geriatric, chronic care management, DOT physicals, physical exams, family medicine, maternal health, family planning, sexually-transmitted disease testing, nursing, health education, immunizations, preventative services, well child exams, acute care, immunizations, lab/x-ray, and women's health). Also offers Certified Application Counselors for the Health Insurance Marketplace. Horizon Health - Yankton Dental offers dental care services include cleanings, dental exams, bridges, crowns, dentures, digital x-rays, emergencies, extractions, fillings, mouth guards, partials, root canals, sealants and spacers.

Horizon Health - Aberdeen is full-service medical clinic offering the following services -preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Provides fully integrated medical and behavioral health care services and is a designated Primary Care Provider for Medicaid and Medicaid Health Home. Delivers patient-centered, team-based care, and provides clinical services for: comprehensive ambulatory medical services for all genders and all ages, acute illness and chronic illness management, immunizations, children's well child exams, adult care, women's health, All Women Count, lab services, school/sport/commercial driver license (CDL) physicals, pre-operative exams, preventative cancer screenings, comprehensive diabetes program, health promotion and education, SD plan & family planning services, HIV & STD testing / STI prevention education, and medication assisted treatment, case management, and certified patient navigators. SDUIH is accredited by the Accreditation Association for Ambulatory Health Care (AAAHC) and is a Federally Qualified Health Center (FQHC). Transportation is available for current patients if needed.

Services include Walk-in Urgent Visits (for both medical and dental), Schedule and same day appointments, Family Practice and Internal Medicine Primary Care for adults, Dental Care for all ages (including teeth cleanings), Sexual and Reproductive Health Services, On-site lab and X-Rays, On-Site Pharmacy, and After-Hours On-Call Provider 365 days a year. Primary and Pediatric Medical Clinic: Most routine medical services and several specialized fields including: physicals, immunizations, preventative medicine, chronic disease management, and counseling. Well child checkups, vaccinations, general pediatric health care. Mental Health: Offers outpatient counseling and psychiatric services, to both children and adults. Case management is offered to adults and families. Dental Clinic: Provides emergency, preventive, and oral health care. Accepts Medicaid, Private Insurance, Medicare, free of charge for the homeless and on a sliding fee scale for uninsured. One Heart Clinic: Providing primary family care to patients with a focus on patients with a primary language of Spanish. Pharmacy: Convenient, on-site location, CHCBH patients are able to fill most of their medications the same day as appointment.

Medical clinic providing health care to people of all ages in the Huron community and surrounding area. Services include gynecology, general surgery, internal medicine, pediatrics, urology, X-ray, laboratory, EKG, family medicine, obstetrics, orthopedics, podiatry, cardiology, and wound care.

Falls Community Health is a family practice medical clinic and dental clinic with emphasis on health promotion and disease prevention. The Community Health Center was established in 1979 with its goal being to remove the barriers, primarily financial, that exist and limit the access of lower income individuals or families seeking primary health care services.  ​Services for the general public include family health, lab radiology, well-child care, immunizations, family planning (including birth control, STD screening and treatment), patient education, and dental care. Services for established clinic patients include outpatient mental health and substance abuse counseling, psychiatry services, transportation assistance (transporter of last resort), and pharmacy assistance to clients of the Falls Community Health Care Clinic.