The Sisseton Wahpeton Oyate of the Lake Traverse Reservation, formerly Sisseton-Wahpeton Sioux Tribe/Dakota Nation, is a federally recognized tribe comprising two bands and two sub-divisions of the Isanti or Santee Dakota people.

Rosebud IHS provides the following mental health services: Individual, couples, marriage, family, and group counseling Psychological testing/mental health evaluation/bio-psycho-socials Medication management (Avel Telepsychiatry) Crisis intervention and Referral Mental health screening Grief and bereavement counseling Terminal illness counseling Utilize Best practice therapies, i.e., Cognitive Behavioral therapy counseling support for co-occurring disorders Teletherapy with Avel Telepsychiatry Also provides consultation to Rosebud Sioux Tribe Alcohol and Drug Abuse Treatment Inpatient and Outpatient Programs, the RST Methamphetamine Inpatient Treatment Program, Wanbli Wiconi Tipi Juvenile Detention Center, RST Adult Correctional Center, RST Courts System, Tiwahe Glu Kinipi Suicide Prevention Program, Wicozani Wakan Suicide Prevention Program, Tiwahe Glu Kinipi Systems of Care Youth and Family Mental Health Program, and local School Districts as requested. Suicide Prevention Specialist programming to assist with prevention activities.

Services include 45 bed hospital, emergency room, Obstetrics, Pediatrics, Surgical, Dental, and Prescription Assistance. Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS.

Considers requests for medical and funeral assistance. Other requests for financial assistance are considered on a case by case basis.

Provides evaluation and treatment for Methamphetamines, including adult residential treatment.

Providing mental health services, Positive Indian Parenting (parenting education for Native American parents), and court approved parent education classes for parents who are separated or divorced. Also provides custody evaluations, mediations, and Social Early Neutral Evaluations (SENE).

Provides shelter for all suffering from domestic violence and/or sexual assault, and their families. In addition to shelter and food, services include: personal and rape advocacy, support groups, legal advocacy and referrals to other service agencies. The Women's Lodge can hold up to 18 adults and children before anyone has to sleep on the floor. Staff can also make arrangements if at full capacity or for other reasons if need be. Two-thirds of residents are usually children since most bring their children with them to protect them from the abuser's violence.

Provides a survivor network of spiritual and emotional support, while increasing community awareness of child sexual abuse and sexual assault. Also offers a book study, one-on-one mentoring, and works on diversity initiatives for Native American Women and Hispanic women.

911 emergency operators, adult detention, juvenile detention, and law enforcement services with jurisdiction within the exterior boundaries of the Cheyenne River Sioux Tribe.

Mental health services with a holistic approach. Experience in working with children, adults, marital counseling, family sessions, group sessions, Native Americans, and veterans. Offers ART (Accelerated Resolution Therapy), social groups for children ages 10-12 and 18-21 who are neurodivergent. Experience in depression, anxiety, PTSD, life coaching, etc. Offers services via telehealth. Same day appointments are available for both counseling and psychiatry services.

Hosts Alcoholics Anonymous (AA), Narcotics Anonymous (NA), and a Grief Support Group.

The Standing Rock Sioux Tribe operates under a constitution approved on April 24, 1959 by the Tribal Council of Standing Rock Sioux Tribe. The Tribal Council consists of a Chairman, Vice-Chairman, a Secretary and fourteen additional Councilmen which are elected by the tribal members. Regular Tribal Council meetings are the first Tuesday, Wednesday, and Thursday of the month. Committee meetings are held the second week of the month. The last Monday of the month is for gaming and other tribal business.

Provides alcohol and substance treatment to the Rapid City (Mni Luzahan) Native American Community and other affiliated tribes in the region. The Native Healing Program utilizes the traditional Native American life ways as a method of healing the spirit. Offers the following: individual counseling, family counseling, substance use counseling, psychological assessments, outpatient substance use treatment, and grief counseling. Also, provides Codependency Workshops, 12 hour DUI class, substance abuse treatment needs assessments, and talking circle. Fully accredited with State of South Dakota for outpatient services. Open to all.

Provides resources, education networking, and events for the LGBTQ+ community. ​Some events include Black Hills Pride Festival, Black Hills Youth Pride, Transgender Day of Remembrance events, Drag Shows, Pride Prom, Transgender Day of Visibility events, Rainbow 5k Color Run, Closet Pop-Ups, and Halloween parties. Also have support groups and volunteer opportunities.

Behavioral health services include outpatient individual, couples, and family counseling, psychological assessment and evaluations (non-court ordered), and case management.

24-hour emergency shelter for women and children that provides crisis services for rape victims, child abuse victims and their non-offending family members, family members of homicide victims, adults molested as children, and victims of elder abuse. Services include accompany victims to hospital and through systems, transportation, advocacy, including criminal justice and court, emergency clothing and other supplies, assistance with protection orders, weekly women's support groups, crisis counseling, referrals and information, and assistance in filing for victim compensation.

The Oglala Lakota or Oglala Sioux, meaning to scatter one's own in Lakota language are one of the seven subtribes of the Lakota people, who along with the Nakota and Dakota, make up the Great Sioux Nation.

The Woodrow Wilson Keeble Memorial Health Care Center is accredited by Joint Commission on Accreditation of Healthcare Organization, Inc. (JCAHO) serving Native American people living in or near Roberts County. Services include Behavioral Health, Dental, Diabetes Care, Health Promotion/Disease Prevention, Laboratory, Nursing, Radiology, Optometry, Pharmacy (Prescription Assistance - Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS), Primary Care, Public Health Nursing, Physical Therapy, Specialty Clinic (OB/GYN), Weight Loss/Nutrition, Well Child Care, Men/Women's Health, and Medication Disposal.

Provides substance and alcohol use prevention, intervention, and continuum of care, behavioral health case management and issues encountered in a conditional behavior environment-(Assimilation). Services provided include alcohol and drug screenings/assessments and substance use and abuse prevention/education/intervention with a cultural approach to healing and cultural identity development.

Horizon Health - Fort Thompson is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Walk-in appointments welcome.

The Cheyenne River Sioux Tribe or Cheyenne River Lakota Nation (Oyate), members include representatives from four of the traditional seven bands of the Lakota, also known as Teton Sioux: the Minnecoujou, Two Kettle (Oohenunpa), Sans Arc (Itazipco) and Blackfoot (Sihásapa).

Providing patient-centered primary care medicine in a variety of settings. Medical services include quick care, wellness physicals, diabetes care (pre-diabetes, obesity, weight loss, and nutrition), medications for Opioid Use Disorder treatment (MOUD), and tribal employee health.

A culturally-appropriate, anonymous, confidential and free service dedicated to serving Native American and Alaska Native impacted by domestic and sexual violence. Advocates take a Native-centered, empowerment based and trauma informed approach to every call, text and chat. Advocates are available 24/7 and offer peer-to-peer support, crisis intervention and safety planning, information and education about domestic and sexual violence, referrals to Native-centered domestic violence, sexual violence service providers, basic information about health options, support locating health facilities or crisis centers trained in the care of sexual assault and forensic exams, and general information about jurisdiction and legal advocacy referrals.

Professional Staff Development Trainings to Agencies and Community, educational events, and presentations surrounding different indigenous educational topics including cultural intelligence, cultural methodology, and healing-informed training to aid in identity development and reconnection to indigenous values. Black Hills Sacred Site Solstice and Equinox onsite ceremony presentations. Trainings available include Lakota Mental Health First-Aid Training (Rick and Ethleen Two Dogs), Tipi Raising Presentation, Buffalo Hide Tanning Presentation, Bow and Arrow Making Presentation, Bapa (Dried Meat) and Wojapi (Wild Fruit) Training, Wokpan Kit Making, Medicinal Tea Making, Inipi (Sweat Lodge) Presentation and Orientation.

Offers the following groups: Bible Study, Recovery Group, and Family and Friends of Addicts, Alcoholics, and Substance Abusers Group.