The Cheyenne River Sioux Tribe or Cheyenne River Lakota Nation (Oyate), members include representatives from four of the traditional seven bands of the Lakota, also known as Teton Sioux: the Minnecoujou, Two Kettle (Oohenunpa), Sans Arc (Itazipco) and Blackfoot (Sihásapa).

Provides a survivor network of spiritual and emotional support, while increasing community awareness of child sexual abuse and sexual assault. Also offers a book study, one-on-one mentoring, and works on diversity initiatives for Native American Women and Hispanic women.

An ambulatory care center with outpatient services. Services include dental care, mental health services, public health nurse, environmental health care, optometry, laboratory, radiology, pharmacy (Prescription Assistance - Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS), podiatry, HIV Clinic, SANE services, and Fitness Center.

The Standing Rock Sioux Tribe operates under a constitution approved on April 24, 1959 by the Tribal Council of Standing Rock Sioux Tribe. The Tribal Council consists of a Chairman, Vice-Chairman, a Secretary and fourteen additional Councilmen which are elected by the tribal members. Regular Tribal Council meetings are the first Tuesday, Wednesday, and Thursday of the month. Committee meetings are held the second week of the month. The last Monday of the month is for gaming and other tribal business.

Providing patient-centered primary care medicine in a variety of settings. Medical services include quick care, wellness physicals, diabetes care (pre-diabetes, obesity, weight loss, and nutrition), medications for Opioid Use Disorder treatment (MOUD), and tribal employee health.

The Sisseton Wahpeton Oyate of the Lake Traverse Reservation, formerly Sisseton-Wahpeton Sioux Tribe/Dakota Nation, is a federally recognized tribe comprising two bands and two sub-divisions of the Isanti or Santee Dakota people.

Offers the following groups: Bible Study, Recovery Group, and Family and Friends of Addicts, Alcoholics, and Substance Abusers Group.

Canku Teca staff counselors provide the following services: Treatment Needs Assessments, Individual counseling, referral services, case management, aftercare/continuing care, state-certified DUI First Offenders class, community outreach and education.

Providing mental health services, Positive Indian Parenting (parenting education for Native American parents), and court approved parent education classes for parents who are separated or divorced. Also provides custody evaluations, mediations, and Social Early Neutral Evaluations (SENE).

24-hour emergency shelter for women and children that provides crisis services for rape victims, child abuse victims and their non-offending family members, family members of homicide victims, adults molested as children, and victims of elder abuse. Services include accompany victims to hospital and through systems, transportation, advocacy, including criminal justice and court, emergency clothing and other supplies, assistance with protection orders, weekly women's support groups, crisis counseling, referrals and information, and assistance in filing for victim compensation.

The Counseling Center offers the following services (all services based on eligibility and priority needs): Substance abuse services include screening, intake, evaluation, referrals, aftercare, primary prevention programs, education, MRT/SBISA classes, and group counseling. ​Mental health services include couples therapy, family therapy, individual therapy, group therapy, Education, Referrals, and Psychological evaluations and services.

Offers a culturally grounded, trauma-informed continuum of care for survivors of domestic violence, sexual assault, and elder abuse within the Cheyenne River Sioux Tribe community and surrounding areas. Core services are survivor-centered and designed to promote safety, empowerment, and long-term stability by including emergency shelter, crisis intervention, and individualized advocacy. Advocates provide confidential support, assist with danger assessments, safety planning, and navigation of tribal and state legal systems, including protection orders, custody filings, and court accompaniment. Medical advocacy is available for hospital, clinic, and SANE exam visits. Staff also support access to victim compensation, transportation, healthcare, employment, childcare, and housing resources. Counseling and support groups help survivors process trauma and rebuild safety. All services are culturally responsive, emphasizing respect, community, and healing. Smudging is offered in the shelter, and clients are connected to tribal elders and cultural mentors for additional traditional healing. A 24-hour crisis line provides immediate, confidential support, while community education promotes healthy relationships, consent awareness, and bystander intervention. The shelter program also hosts Domestic Violence and Sexual Assault community education/awareness/prevention events to the public or organizations within the community.

A culturally-appropriate, anonymous, confidential and free service dedicated to serving Native American and Alaska Native impacted by domestic and sexual violence. Advocates take a Native-centered, empowerment based and trauma informed approach to every call, text and chat. Advocates are available 24/7 and offer peer-to-peer support, crisis intervention and safety planning, information and education about domestic and sexual violence, referrals to Native-centered domestic violence, sexual violence service providers, basic information about health options, support locating health facilities or crisis centers trained in the care of sexual assault and forensic exams, and general information about jurisdiction and legal advocacy referrals.

Provides substance and alcohol use prevention, intervention, and continuum of care, behavioral health case management and issues encountered in a conditional behavior environment-(Assimilation). Services provided include alcohol and drug screenings/assessments and substance use and abuse prevention/education/intervention with a cultural approach to healing and cultural identity development.

Mental health services with a holistic approach. Experience in working with children, adults, marital counseling, family sessions, group sessions, Native Americans, and veterans. Offers ART (Accelerated Resolution Therapy), social groups for children ages 10-12 and 18-21 who are neurodivergent. Experience in depression, anxiety, PTSD, life coaching, etc. Offers services via telehealth. Same day appointments are available for both counseling and psychiatry services.

Providing mental health services, Positive Indian Parenting (parenting education for Native American parents), and court approved parent education classes for parents who are separated or divorced. Also provides custody evaluations, mediations, and Social Early Neutral Evaluations (SENE).

Provides the following services - emergency room, inpatient care, comprehensive primary care, Primary Care Medical Home (PCMH), behavioral health, adult and pediatric dental, eye clinic, radiology, laboratory, nursing, pharmacy, public health nursing, dietician, and telehealth (including behavioral health, internal medicine, and rheumatology).

Horizon Health - Fort Thompson is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Walk-in appointments welcome.

Professional Staff Development Trainings to Agencies and Community, educational events, and presentations surrounding different indigenous educational topics including cultural intelligence, cultural methodology, and healing-informed training to aid in identity development and reconnection to indigenous values. Black Hills Sacred Site Solstice and Equinox onsite ceremony presentations. Trainings available include Lakota Mental Health First-Aid Training (Rick and Ethleen Two Dogs), Tipi Raising Presentation, Buffalo Hide Tanning Presentation, Bow and Arrow Making Presentation, Bapa (Dried Meat) and Wojapi (Wild Fruit) Training, Wokpan Kit Making, Medicinal Tea Making, Inipi (Sweat Lodge) Presentation and Orientation.

Services provided include: ambulatory clinic, laboratory, X-Ray, pharmacy, dental unit, public health nursing, diabetes care, fitness program, mental health services, and optometry services. Specialty care clinics available: cardiology, wound care, OBGYN Prescription Assistance - Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS.

Provides shelter for all suffering from domestic violence and/or sexual assault, and their families. In addition to shelter and food, services include: personal and rape advocacy, support groups, legal advocacy and referrals to other service agencies. The Women's Lodge can hold up to 18 adults and children before anyone has to sleep on the floor. Staff can also make arrangements if at full capacity or for other reasons if need be. Two-thirds of residents are usually children since most bring their children with them to protect them from the abuser's violence.

Provides resources, education networking, and events for the LGBTQ+ community. ​Some events include Black Hills Pride Festival, Black Hills Youth Pride, Transgender Day of Remembrance events, Drag Shows, Pride Prom, Transgender Day of Visibility events, Rainbow 5k Color Run, Closet Pop-Ups, and Halloween parties. Also have support groups and volunteer opportunities.

Outpatient medical clinic, provides general family practice medicine. Prescription Assistance - Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS. Services include comprehensive primary care, Primary Care Medical Home (PCMH), behavioral health, dental, laboratory, nursing, pharmacy, public health nursing, radiology, dietitian, and telehealth (including behavioral health, internal medicine, and rheumatology).

Considers requests for medical and funeral assistance. Other requests for financial assistance are considered on a case by case basis.

Individual and couples therapy for adults dealing with life transitions, healing from trauma and/or abuse, restoring difficult relationships, or looking for balance and support in their lives. Individual therapy for adolescents dealing with trauma or behavior issues. Assessment and therapy for those engaged in addictive behaviors, and also for those who love them. Experienced in serving the Native American community, particularly in the areas of historical trauma and grief.